Plummer's disease or tirotoksicheskaya adenoma is a benign neoplasm of the thyroid gland, which leads to an increase in the body levels of thyroid hormones. In this case, the body falls into a special state - gipertiroz, which leads to an overabundance of hormones thyroxine and triiodothyronine levels. In turn, these hormones block the production of the hormone TSH (thyroid-stimulating hormone of the pituitary gland), which regulates the normal functioning of the thyroid gland. Most often, the disease affects women, men and children suffer Plummer's disease is about four times less. Usually tirotoksicheskaya adenoma is small (about 2-3 inches) and usually develops only one node, but there are also options for multisite. To date, the main cause of the disease Plummer, physicians consider the mutation of a gene that triggers the accumulation of cAMP in the cell and thus causes the thyroid gland to produce hormones continuously.

  The symptomatology of an illness of Plammer is similar to symptoms of a diffusion toxic craw and is expressed by the following symptoms:

  • weakness;
  • short wind;
  • causeless decrease in weight of a body;
  • intolerance of a heat;
  • vibrating arrhythmia or sinusovy tachycardia.

   Distinctions consist in less expressed influence on cardiovascular system, less fast development of a disease and bigger age of patients. Diagnostics of an illness of Plammer in Israel includes:

  • Survey of the expert which can grope characteristic knot in one of lateral shares of gland;
  • Radio isotope diagnostics and ultrasonic research of a thyroid gland precisely to define situation and the sizes of the found knot;
  • laboratory researches for definition of sharply lowered TTG and raised triiodothyronine against normal thyroxine.

  Treatment of this disease Israel is carried out by only a surgical method. In hard cases before surgery also carry out treatment thyrostatics. To patients is more senior than forty years under control of ultrasonography carry out treatment by injections of alcohol or radioactive iodine directly to a place of localization of adenoma. At the surgery, remote knot subject to the most thorough histologic research. The disease forecast at the majority of patients at Plammer's illness favorable and an illness can become complicated only in case of malignant regeneration which meets quite seldom.

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